Element 5 NMN

It's completely up to you — choose a time that fits your routine.

Many customers prefer to take NMN in the morning, but it can be taken at any time of day.

NMN can be taken with or without food; a glass of water is all you need.

Once ingested, NMN is absorbed into the bloodstream and transported into cells through a protein called SLC12A8. Inside the cell, it is converted into NAD+, a coenzyme involved in many biological processes.

This was described in a 2019 study published in Nature Metabolism by Dr. Shin-ichiro Imai's team, which suggested NMN can be taken up directly by cells without first converting to NR.

Research continues into how NMN uptake varies across tissues, particularly in the brain, muscles, and liver.

NMN doesn't typically produce fast or obvious effects and experiences can vary from person to person.

Some studies have explored changes in NAD+ levels after consistent use for 8 to 12 weeks. Some users track their progress using intracellular NAD+ tests, taken before and after supplementation.

The NAD+ molecule is too large to pass through cell membranes efficiently. NMN, being smaller and transported directly into cells, is a more effective precursor.

The recommended dose for Element 5 NMN is 500 mg per day (one capsule), taken in the morning with water.

Study Evidence: A study in Frontiers in Nutrition showed 250 mg of NMN nearly doubled NAD+ levels over 12 weeks. Another study observed significant NAD+ increases with 300–900 mg/day, with improvements in muscle endurance at higher doses.

NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme found in every living cell. It plays a key role in energy metabolism and important biological pathways like sirtuin activation.

Scientists continue to study NAD+ for its role in maintaining healthy cellular function, especially as levels are known to decline with age.

NR (Nicotinamide Riboside) is another NAD+ precursor that converts into NMN in the body before eventually forming NAD+.

NMN enters the NAD+ biosynthesis pathway at a later stage, meaning it may bypass one conversion step — making it a more direct precursor.

NAD+ is a coenzyme found in all living cells. It plays a central role in cellular energy metabolism and processes related to cellular maintenance and stress response.

Research is ongoing into how NAD+ interacts with proteins like sirtuins, studied for their role in healthy aging and cell regulation.

NMN is found in small amounts in edamame, broccoli, cabbage, avocados, and cucumbers — but the natural content is very low.

Edamame contains about 1.8mg of NMN per 100g. To reach a 500mg daily dose from food alone you'd need:

• 26.5kg of edamame
• 40kg of cucumber
• 80kg of avocado
• 55kg of cabbage

Yes! Open the capsule and pour into water. NMN may sink in small clumps initially (completely normal — it's compacted). Stir and it will turn slightly cloudy as it dissolves.

If left to settle, bubbles clear from the bottom up. NMN doesn't need to be fully dissolved to be effective — purely personal preference.

This is one of the most common questions we get — and we understand why. NMN is a precursor to NAD+, supporting NAD+ levels over time, not creating instant effects.

Everyone responds differently. Some feel a difference quickly; others don't feel anything — but that doesn't mean it's not working at a cellular level.

We suggest a more objective approach rather than going by feel:

• Take an NAD+ test before you start
• Re-test after 60–90 days

Element 5 is designed for adults who want to support their long-term health, energy and vitality.

Some customers prefer subscriptions so they never run out of their supplements. Subscription options are flexible and can be managed or cancelled at any time.

If you have any questions, our team is always happy to help. You can reach us through the contact page and we'll get back to you as quickly as possible.

Yes. Quality and transparency are extremely important to us. Our ingredients and finished products are tested to ensure they meet our standards for purity and safety. All reports are available to view and download on the relevant product pages.

Many customers include Element 5 products as part of a broader supplement routine. If you are unsure about combining supplements, it's always best to consult a healthcare professional.

Every order comes with a 120 Day Guarantee as we want customers to feel confident trying Element 5. If you have any issues with your order, our support team is available to help and make things right.

Orders are typically processed same or next day (Monday to Friday). Shipping times will vary depending on your location, but most customers receive their order within a few working days.

Our supplements are manufactured in the UK in facilities that are GMP certified. Every batch is produced under controlled conditions to ensure consistency and purity, then 3rd party tested.