NMN
NMN — the precursor
to NAD⁺.
Nicotinamide Mononucleotide is a naturally occurring molecule that your cells convert directly into NAD⁺ — the coenzyme behind energy metabolism, cellular maintenance and the activation of sirtuins.
What is Nicotinamide Mononucleotide?
NMN is a naturally occurring molecule made from ribose and nicotinamide. It acts as a direct precursor to NAD⁺ — a coenzyme found in all living cells, involved in energy metabolism and core cellular processes.
NMN is a precursor to NAD⁺ — a molecule involved in various cellular processes, including the activation of sirtuins, which are being studied for their role in cellular maintenance and stress response.
How NMN becomes NAD⁺
Based on a 2019 Nature Metabolism study from Dr Shin-ichiro Imai's team, NMN follows a precise route from your glass to your cells.
NAD⁺ naturally declines with age
Move the slider to see how cellular NAD⁺ availability is generally understood to change across the lifespan — and why a precursor strategy is studied.
Illustrative trend only. As NAD⁺ availability changes, the cellular processes it powers — energy metabolism, DNA repair signalling and sirtuin activity — are studied as part of healthy ageing research.
The sofa through the doorway
The NAD⁺ molecule is too large to cross cell membranes efficiently. NMN is smaller — it uses dedicated transporters and is reassembled into NAD⁺ exactly where it's needed.
Six human clinical trials
Real peer-reviewed research on NMN supplementation. Filter by cohort, then tap any study to reveal its findings.
One capsule. A clinically-studied dose.
Element 5 delivers 500 mg of NMN per capsule, taken once daily with water — sitting within the ranges examined across human trials.
Per Element 5 capsule
Once daily, with water. Research from Frontiers in Nutrition observed increased NAD⁺ after 12 weeks at 250 mg — and trials note dose-dependent effects, with larger doses yielding more pronounced increases.
Doses studied across trials
Where Element 5's dose sits against the ranges examined in published human research.
Co-founder Jonny Bradley shares his protocol
Jonny had been taking NMN for 18 months, trying products from various companies. Time and again he met misleading claims and questionable transparency — so he built Element 5. Now he shares his exact healthcare protocols: a deep look into his life, habits and routines that you can follow along with, for free.
Recommended reading
The longevity and NAD⁺ science that shaped the protocol.
NMN, answered
"I've used the whole bottle and noticed a marked improvement in energy levels, skin and hair. Already bought more."
— Verified Element 5 customer
Rebuild NAD⁺ from the inside out.
Start with the science that powers the protocol — Element 5 NMN — sourced and shared with full transparency.
This content is informational only and not medical advice. References to the NMN–NAD⁺ relationship are based on third-party studies and are not authorised health claims. Always consult a qualified healthcare provider before changing your supplement, diet or exercise regimen.